Wang XM1, Dong Z1, Schwarz S2, Zhu Y1, Hua X1, Zhang Y1, Liu S3, Zhang WJ3

Antimicrob Agents Chemother. 2017 Jul 3

Abstract

Thirty-nine fosfomycin-resistant E. coli isolates carrying fosA3 were obtained from pigs, chickens, dairy cows and staff in four Northeastern provinces of China during 06/2015-04/2016. The fosA3 was co-located with blaCTX-M genes on conjugative plasmids of the incompatibility groups IncN (n=12), IncN-F33:A-:B- (n=2), IncF33:A-:B- (n=14), IncF14:A-:B- (n=2), and IncI1/ST136 (n=9). Four different genetic contexts offosA3 were detected among the 39 E. coli isolates. Three potential epidemic plasmids circulated among E. coli strains from this region.