1、个人简历
罗玉子,女,博士,副研究员,硕士研究生导师,哈兽研猪烈性传染病创新团队科研骨干。主要从事非洲猪瘟、猪瘟和伪狂犬病等猪重要疫病的病原学和流行病学研究、新型诊断试剂研制。先后主持国家自然科学基金青年基金项目和面上项目、十三五国家重点研发计划项目子课题、农业部非洲猪瘟防控技术集成项目子课题等项目8项,累计经费300多万元;以第一完成人申请国家发明专利2项、获得国家发明专利授权1项;先后在Vet Microbiol、Antiviral Res、Transbound Emerg Dis等国际学术刊物发表第一作者SCI论文15篇、其他作者SCI论文40余篇;研发非洲猪瘟和猪瘟诊断试剂盒4个;申报新兽药注册4项。
2、联系方式
(1)研究方向:动物传染病及其病原分子流行病学
(2)电话:18724613386
(3)邮箱:luoyuzi@caas.cn
(4)所在单位:保定市金诺兽药研究所
(5)通讯地址:哈尔滨市香坊区哈平路678号
3、教育经历
1997.09-2001.06 延边大学 兽医学专业 学士
2001.09-2004.06 延边大学 预防兽医学专业 硕士
2009.04-2012.03 日本国立带广畜产大学 畜产卫生学专业 博士
4、工作经历
2004.07-2005.08 延边大学农学院 助教
2005.09-2008.08 韩国首尔大学兽医学院 研究助理
2008.10-2009.03 日本国立原虫病研究中心 研究助理
2012.03-2017.12 保定市金诺兽药研究所 助理研究员
2018.01-至今 保定市金诺兽药研究所 副研究员
5、承担项目
1.国家自然科学基金面上项目:猪瘟病毒流行毒株逃逸C株疫苗诱导的中和抗体的分子机制(31873015,2019.01-2022.12),60万元,主持;
2.国家自然科学基金青年基金项目:与猪瘟兔化弱毒疫苗株E2蛋白相互作用的家兔脾细胞蛋白的筛选和功能鉴定(31402194,2015.01-2017.12),24万元,主持;
3.农业部非洲猪瘟应急项目:非洲猪瘟防控技术集成项目子课题(2018.08-2019.08),80万元,主持;
4.国家重点研发计划项目(动物重大疫病新概念防控产品研发)子课题:自组装纳米颗粒展示猪瘟病毒表位的新型口服疫苗研发(2017YFD051105,2017.07-2020.12),58万元,主持;
5.国家重点研发计划项目(烈性外来动物疫病防控技术研发)子课题:免疫增强型非洲猪瘟病毒基因工程亚单位疫苗的研制(2017YFD0502303,2017.07-2020.12),50万元,主持;
6.国家重点研发计划项目(猪重要疫病的诊断与检测新技术研究)子课题:猪临床样品未知病原检测技术研究(2016YFD0500705,2016.07-2020.12),35万元,主持;
7.黑龙江省自然科学基金面上项目:2.1d基因亚型猪瘟病毒抗原性变异的分子基础及C株疫苗对其免疫保护效果评价(C2017074,2017.10-2020.10),6万元,主持;
8.哈尔滨市科技创新人才(青年后备人才项目):猪瘟病毒E2蛋白在酵母系统中的高效表达及其抗体监测ELISA试剂盒的研制(2015RAQYJ064,2016.01-2017.12),4万元,主持。
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6、代表论文(#,并列第一作者)
1. Xintao Zhou#, Nan Li#, Yuzi Luo#, Ye Liu, Faming Miao, Teng Chen, Shoufeng Zhang, Peili Cao, Xiangdong Li, Kegong Tian, Hua-Ji Qiu, Rongliang Hu. Emergence of African swine fever in China, 2018. Transboundary and Emerging Diseases. 2018, 65: 1482-1484.
2. Shengwei Ji#, Yuzi Luo#, Tengteng Zhang#, Lina Shao, Xing-Yu Meng, Yimin Wang, Yao Gao, Yongfeng Li, Su Li, Yuan Sun, Xin Jin, Hua-Ji Qiu. An improved indirect ELISA for specific detection of antibodies against classical swine fever virus based on structurally designed E2 protein expressed in suspension mammalian cells. Archives of Virology. 2018, 163(7):1831-1839.
3. Yuzi Luo, Shengwei Ji, Yan Liu, Jian-Lin Lei, Shui-Li Xia, Yimin Wang, Ming-Liang Du, Lina Shao, Xing-Yu Meng, Mo Zhou, Yuan Sun, Hua-Ji Qiu. Isolation and characterization of a moderately virulent classical swine fever virus emerging in China. Transboundary and Emerging Diseases. 2017, 64(6): 1848-1857.
4.Yuzi Luo, Shengwei Ji, Jian-Lin Lei, Guang-Tao Xiang, Yan Liu, Yao Gao, Xing-Yu Meng, Guanglai Zheng, En-Yu Zhang, Yimin Wang, Ming-Liang Du, Yongfeng Li, Su L, Xi-Jun He, Yuan Sun, Hua-Ji Qiu. Efficacy evaluation of the C-strain-based vaccines against the subgenotype 2.1d classical swine fever virus emerging in China. Veterinary Microbiology. 2017, 201:154-161.
5. Yuzi Luo, Stella A. Atim, Lina Shao, Chrisostom Ayebazibwe, Yuan Sun, Yan Liu, Shengwei Ji, Xing-Yu Meng, Su Li, Yongfeng Li, Charles Masembe, Karl St?hl, Frederik Widén, Lihong Liu, Hua-Ji Qiu. Development of an updated PCR assay for detection of African swine fever virus. Archives of Virology. 2017, 162(1): 191-199.
6. Yuan Sun#, Yuzi Luo#, Chun-Hua Wang#, Jin Yuan, Na Li, Kun Song, Hua-Ji Qiu HJ. Control of swine pseudorabies in China: Opportunities and limitations. Veterinary Microbiology. 2016, 183:119-124.
7. Yuzi Luo, Lin Li, Sophia Austermann-Busch, Mei Dong, Jingjing Xu, Lina Shao, Jian-Lin Lei, Na Li, Wen-Rui He, Bibo Zhao, Su Li, Yongfeng Li, Lihong Liu, Paul Becher, Yuan Sun, Hua-Ji Qiu. Enhanced expression of the Erns protein of classical swine fever virus in yeast and its application in an indirect enzyme-linked immunosorbent assay for antibody differentiation of infected from vaccinated animals. Journal of Virological Methods. 2015, 222: 22-27.
8. Yuzi Luo, Na Li, Xin Cong, Chun-Hua Wang, Min Du, Lin Li, Bibo Zhao, Jin Yuan, Dan-Dan Liu, Su Li, Yongfeng Li, Yuan Sun, Hua-Ji Qiu. Pathogenicity and genomic characterization of a pseudorabies virus variant isolated from Bartha-K61-vaccinated swine population in China. Veterinary Microbiology. 2014, 174(1-2): 107-115.
9. Yuzi Luo, Su Li, Yuan Sun, Hua-Ji Qiu. Classical swine fever in China: a minireview. Vet Microbiol. 2014, 172(1-2):1-6.
10. Long Yin#, Yuzi Luo#, Bo Liang, Fei Wang, Min Du, Valery A. Petrenko, Hua-Ji Qiu, Aihua Liu. Specific ligands for classical swine fever virus screened from landscape phage display library. Antiviral Research. 2014, 109:68-71.
11. Yuzi Luo, Mohamad Alaa Terkawi, Honglin Jia, Gabriel Oluga Aboge, Youn-Kyoung Goo, Shinuo Cao, Yan Li, Longzheng Yu, Hideo Ooka, Ketsarin Kamyingkird, Tatsunori Masatani, Shoufa Zhang, Yoshifumi Nishikawa, Ikuo Igarashi, Xuenan Xuan. A double antibody sandwich enzyme-linked immunosorbent assay for detection of secreted antigen 1 of Babesia microti using hamster model. Experimental Parasitology. 2012, 130(2):178-182.
12. Yuzi Luo, Mohamad Alaa Terkawi, Honglin Jia, Gabriel Oluga Aboge, Youn-Kyoung Goo, Shinuo Cao, Yan Li, Longzheng Yu, Hideo Ooka, Ketsarin Kamyingkird, Tatsunori Masatani, Shoufa Zhang, Yoshifumi Nishikawa, Ikuo Igarashi, Xuenan Xuan. Identification and characterization of a novel secreted antigen 1 of Babesia microti and evaluation of its potential use in enzyme-linked immunosorbent assay and immunochromatographic test. Parasitology International. 2011, 60(2):119-125.
13. Hye Kwon Kim#, Yuzi Luo#, Hyung Joon Moon, Seong Jun Park, Hyun Ok Keum, Semi Rho, Bong Kyun Park. Phylogenetic and recombination analysis of genomic sequences of PCV2 isolated in Korea. Virus Genes. 2009, 39(3):352-358.
7、专利
1.仇华吉,罗玉子,孙元,孟星宇,李素,李永锋,检测非洲猪瘟病毒的PCR引物、试剂盒及其应用,ZL201610183350.5;
2.仇华吉,孙元,罗玉子,李素,李永锋,伪狂犬病病毒变异株双基因缺失毒株及其构建方法和应用,ZL201410105058.2.
8、获得奖励
1.猪瘟病毒复制的分子调控机制与防控理论创新,中国农业科学院,杰出科技创新奖,仇华吉,李素,李永锋,李连峰,孙元,罗玉子,2018年.
(2019年6月更新)